Insulin-like growth factor-1 Long R3 (IGF-1 LR3) is a modified version of the naturally occurring insulin-like growth factor-1 (IGF-1). It is a synthetic peptide hormone that has been shown to have anabolic effects on muscle tissue, meaning it helps promote muscle growth and repair. IGF-1 LR3 differs from regular IGF-1 in that it has an additional 13 amino acids on its N-terminal end, which increases its half-life and bioavailability in the body. This makes it more effective at promoting muscle growth than regular IGF-1. Insulin-like growth factor plays a crucial role in cell growth and division, particularly in skeletal muscle cells. When IGF-1 biczxznds to its receptor on muscle cells, it activates signaling pathways that promote protein synthesis and inhibit protein breakdown. This results in an increase in muscle mass and a reduction in muscle wasting or atrophy.
IGF-1 stimulates the proliferation and differentiation of satellite cells, which are responsible for repairing damaged muscle tissue after exercise or injury. Overall, insulin-like growth factor is essential for maintaining healthy muscle tissue and promoting muscle growth through its effects on cell division and protein synthesis.
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